班級：醫學物理暨影像科學研究所 碩士班 (英語授課) 學分：3 選修(兩年開一次; 96, 97學年度上學期起開課, 之後單數年度開課！) 時間：星期三 9:10-12:00 (三小時) 地點：長庚大學-醫學大樓 討論室(三) 作業：請同學準備英文口頭報告，內容以自己實驗題目與分子影像相關做報告！報告前請將power point寄到老師的信箱，一個人請在40分鐘內完成報告，其他同學有10分鐘時間可以提問！ (Email: lin4857@adm.cgmh.org.tw) PS: 請點選授課內容下載講義 (PS: 遵守智慧財產權 文件下載須登入，帳號請找小老師)，last update 2011-01-21.
| 日期 | 授課內容 | 老師 | 1 | 2010-09-15 | Introduction | 講義下載 | 林昆儒醫師 | 2 | 2010-09-20 | Biomarker and radiotracer
| 魏孝萍老師 | 3 | 2010-09-28 | Receptor binding assay / Autoradiography
| 林昆儒醫師 | 4 | 2010-10-04 | The applications of fluorescence and bioluminescence
| 張祐銓醫師 | 5 | 2010-10-12 | The basics of optical technology
| 沈家瑞老師 | 6 | 2010-10-19 | Oral presentation | 林昆儒醫師 | 7 | 2010-10-26 | The basics of tomography-based imaging
| 杜書儒老師 | 8 | 2010-11-01 | Magnetic Resonance Imaging (MRI) and its clinical applicaitons | 王俊杰老師 | 9 | 2010-11-09 | MicroPET/SPECT instrumentation / animal handling | 林昆儒醫師 | 10 | 2010-11-16 | Molecular Image application in human studies | 閻紫宸醫師 | 11 | 2010-11-23 | Imaging application for BBB opening | 劉浩澧老師 | 12 | 2010-11-30 | Oral presentation | 林昆儒醫師 | 13 | 2010-12-07 | Image reconstruction / PMOD application | 蕭穎聰老師 | 14 | 2010-12-14 | Kinetic analysis (I) / PMOD application | 蕭穎聰老師 | 15 | 2010-12-21 | Kinetic analysis (II) / PMOD application | 林昆儒醫師 | 16 | 2010-12-28 | Animal PET application / Quantification analysis | 林昆儒醫師 | 17 | 2011-01-04 | Multimodality study design | 林昆儒醫師 | 18 | 2011-01-13 | 期末考 | 林昆儒醫師
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Books: (遵守智慧財產權，請自學校主機下載) Book Title - Molecular Imaging DOI - 10.1007/b138116 Editor - A. A. Bogdanov, K. Licha Book Title - Molecular Imaging I (ISSN 0171-2004) DOI - 10.1007/978-3-540-72718-7 Editor - Wolfhard Semmler, Markus Schwaiger Book Title - Molecular Imaging II (ISSN 0171-2004) DOI - 10.1007/978-3-540-77496-9 Editor - Wolfhard Semmler, Markus Schwaiger Book Title - Quantitative Analysis in Nuclear Medicine Imaging DOI - 10.1007/b107410 Editor - Habib Zaidi Web sources: - MRI lecture
Laurie Hall video recorded in 1998. Nuclear magnetic resonance imaging (MRI) provides a powerful means of not only distinguishing between different types of tissue but also of identifying whether the tissues are normal or diseased. (來源 | Vega ) 請使用Realplayer  播放影片  MIT OpenCourseWare | Health Sciences and Technology | HST.512 Genomic Medicine, Spring 2004 | Lecture Notes This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. - MIT OpenCourseWare | Brain and Cognitive Sciences | 9.14 Brain Structure and its Origins Spring 2005 | Lecture Notes
This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution.
Lectures require Macromedia Flash and JavaScript enabled on your browser. Molecular Imaging is the new frontier in radiology. The Primer on Molecular Imaging and the lectures available on the ACR Campus introduce molecular imaging and its importance to the practice of radiology. The ACR established the Commission on Molecular Imaging in the fall of 2001. This initiative recognized the growing importance and long-term potential of molecular imaging methods in the clinical practice of radiology. The commission has the broad charge to undertake activities that promote molecular imaging as part of radiology practice and to promote undertakings that will help ensure that radiologists have the knowledge, information, and skills to successfully incorporate emerging molecular imaging methods in their practices. The potential for molecular imaging is enormous, largely on the basis of the ability to harvest scientific progress in molecular biology for use in designing novel molecular imaging pharmaceuticals. In fact, if we are now in the age of molecular medicine, molecular imaging will play a significant part in the advancement of radiology for the foreseeable future. |
| Why Should Radiologists Learn About Molecular Imaging? Presenter(s): King C. Li, MD, MBA Length: 30 Minutes 12 Seconds | Basic Molecular Biology: From DNA to Proteins Presenter(s): Sunil Pandit, PhD Length: 44 Minutes 38 Seconds View Lecture | | Molecular Imaging in Cancer: Linking Biology, Function, and Clinical Applications Presenter(s): James P. Basilion, PhD Length: 50 Minutes 1 Seconds View Lecture | Molecular Probes for MR Signal Amplification Presenter(s): Alexei Bogdanov, PhD Length: 29 Minutes 27 Seconds View Lecture | | Multimodality Molecular Imaging of Living Subjects Presenter(s): Sanjiv Sam Gambhir MD, PhD Length: 58 Minutes 41 Seconds View Lecture | Tracer Kinetic Modeling for Quantitative Molecular Imaging Presenter(s): Richard E. Carson, PhD Length: 36 Minutes 18 Seconds View Lecture | | Equipment for Imaging Molecular Processes Presenter(s): David Thomasson, PhD Length: 1 Hour 7 Minutes 32 Seconds View Lecture | Molecular Imaging with Positron Emission Tomography Presenter(s): Martin G. Pomper, MD, PhD Length: 30 Minutes 49 Seconds View Lecture | | SPECT and Molecular Imaging Presenter(s): Steven Larson, MD Length: 46 Minutes 32 Seconds View Lecture | Introduction to Optical Imaging Presenter(s): Umar Mahmood, MD, PhD Length: 62 Minutes 22 Seconds View Lecture | | Preclinical and Clinical Applications of MR in Cancer Presenter(s): Zaver Bhujwalla, PhD Length: 35 Minutes 56 Seconds View Lecture | Ultrasound Molecular Imaging and Drug Delivery Presenter(s): Katherine Ferrara, PhD Length: 37 Minutes 29 Seconds
| | Molecular Imaging in Basic Research Presenter(s): David Piwnica-Worms, MD, PhD Length: 1 Hour 13 Minutes 5 Seconds View Lecture | Molecular Imaging: Overview and Future Directions Presenter(s): James H. Thrall MD Length: 35 Minutes 9 Seconds View Lecture |
Reference: - Matthew A. Kupinski, Harrison H Barrett, Small-Animal SPECT Imaging, Springer; 1 edition 2005.
- Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin, The Laboratory Rat. Academic Press; Second edition, 2005
- Miles N. Wernick and John N. Aarsvold. Emission Tomorgaphy : The Fundamentals of PET and SPECT. Elsevier, 2006.
- Small animal SPECT and SPECT/CT: Important tools for preclinical investigation J Nucl Med 2008 49: 1651-1663 (DOI: 10.2967/jnumed.108.055442). (Ref )
- Imaging of Apoptosis J Nucl Med 2008 49: 1573-1576 (DOI: 10.2967/jnumed.108.052803). (Ref )
- Revised guides for organ sampling and trimming in rats and mice (Ref )
- Pathbase web site: Pathbase is a database of histopathology photomicrographs and macroscopic images derived from mutant or genetically manipulated mice. ( Ref ) cited from "European mutant mouse pathology database (Pathbase), Pathbase web site, University of Cambridge, World Wide Web (http://www.pathbase.net)"
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